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Yushi Inoue Selected Research

stiripentol

1/2021Long-term safety and effectiveness of stiripentol in patients with Dravet syndrome: Interim report of a post-marketing surveillance study in Japan.
1/2020Impact of CYP2C19 Phenotypes on Clinical Efficacy of Stiripentol in Japanese Patients With Dravet Syndrome.
1/2017Add-on stiripentol elevates serum valproate levels in patients with or without concomitant topiramate therapy.
7/2015Long-term safety and efficacy of stiripentol for the treatment of Dravet syndrome: A multicenter, open-label study in Japan.
5/2014Effectiveness of add-on stiripentol to clobazam and valproate in Japanese patients with Dravet syndrome: additional supportive evidence.
7/2012Efficacy of stiripentol in hyperthermia-induced seizures in a mouse model of Dravet syndrome.
11/2009Stiripentol open study in Japanese patients with Dravet syndrome.

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Yushi Inoue Research Topics

Disease

42Epilepsy (Aura)
10/2022 - 03/2003
28Seizures (Absence Seizure)
01/2022 - 03/2003
12Myoclonic Epilepsies (Myoclonic Encephalopathy)
01/2021 - 11/2009
8Drug Resistant Epilepsy
10/2022 - 03/2004
6Hyperammonemia
12/2019 - 09/2012
5Body Weight (Weight, Body)
01/2022 - 04/2015
5Partial Epilepsies (Epilepsy, Partial)
02/2020 - 07/2011
4Sleepiness
11/2016 - 11/2012
4Generalized Epilepsy
10/2015 - 03/2004
3Temporal Lobe Epilepsy
01/2022 - 01/2012
3Brain Diseases (Brain Disorder)
01/2019 - 11/2012
3Encephalitis (Encephalitis, Rasmussen)
09/2013 - 06/2012
2Focal cortical dysplasia of Taylor
01/2022 - 07/2021
2Focal Cortical Dysplasia
01/2022 - 09/2017
2Autism Spectrum Disorder
01/2019 - 11/2018
2Intellectual Disability (Idiocy)
01/2019 - 01/2018
2Nasopharyngitis
12/2018 - 05/2014
2Frontal Lobe Epilepsy (Epilepsy, Supplementary Motor)
01/2018 - 09/2017
2Spasm (Spasms)
11/2016 - 07/2011
2Febrile Seizures (Febrile Seizure)
10/2015 - 03/2004
2Ataxia (Dyssynergia)
07/2015 - 05/2014
2Myoclonus (Nocturnal Myoclonus)
05/2010 - 06/2009
1Cerebrovascular Disorders (Cerebrovascular Occlusion)
02/2020
1Craniosynostoses (Craniosynostosis)
01/2020
1Chronic Disease (Chronic Diseases)
01/2020
1Hyponatremia
12/2019
1Cardiac Arrhythmias (Arrythmia)
02/2019
1Ventricular Tachycardia
02/2019
1Inflammation (Inflammations)
12/2018
1Fever (Fevers)
12/2018
1Schizophrenia (Dementia Praecox)
11/2018
1Juvenile Myoclonic Epilepsy
01/2018
1Tonic-Clonic Epilepsy (Epilepsy, Tonic Clonic)
01/2018
1Autistic Disorder (Autism)
01/2018
1Dyslipidemias (Dyslipidemia)
11/2016
1Dizziness (Lightheadedness)
11/2016
1Hypercapnia
06/2016
1Epileptic Syndromes
06/2016

Drug/Important Bio-Agent (IBA)

15Phenytoin (Dilantin)FDA LinkGeneric
02/2020 - 01/2012
14Anticonvulsants (Antiepileptic Drugs)IBA
07/2021 - 11/2009
13Valproic Acid (Depakote)FDA LinkGeneric
02/2020 - 01/2012
10perampanelIBA
10/2022 - 01/2017
9Phenobarbital (Luminal)FDA Link
12/2019 - 01/2012
8Pharmaceutical PreparationsIBA
10/2022 - 01/2004
8Carbamazepine (Tegretol)FDA LinkGeneric
12/2019 - 01/2012
7stiripentolIBA
01/2021 - 11/2009
7Lamotrigine (Lamictal)FDA LinkGeneric
05/2016 - 09/2011
6Clobazam (HR 376)IBA
01/2020 - 07/2012
6Voltage-Gated Sodium ChannelsIBA
01/2018 - 03/2004
5Topiramate (Topamax)FDA LinkGeneric
01/2018 - 09/2012
5AmmoniaIBA
12/2015 - 09/2012
4EnzymesIBA
12/2018 - 01/2012
3LacosamideFDA Link
10/2021 - 11/2016
3Levetiracetam (Keppra)FDA LinkGeneric
02/2020 - 10/2015
3Cytochrome P-450 CYP2C19IBA
01/2020 - 06/2013
3Proteins (Proteins, Gene)FDA Link
12/2018 - 03/2004
3Nonsense Codon (Nonsense Mutation)IBA
01/2018 - 03/2003
2Sirolimus (Rapamycin)FDA Link
01/2022 - 07/2021
2SodiumIBA
12/2019 - 02/2019
2AlbuminsIBA
12/2018 - 11/2012
2Ethosuximide (Zarontin)FDA LinkGeneric
01/2018 - 11/2012
2Carbonic Anhydrase InhibitorsIBA
12/2015 - 06/2013
2gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA
07/2015 - 05/2014
2Uridine Diphosphate (UDP)IBA
06/2015 - 06/2014
2Glucuronosyltransferase (UDP Glucuronosyltransferase)IBA
06/2015 - 06/2014
2Cytochrome P-450 CYP2C9IBA
04/2015 - 06/2014
2Clonazepam (Rivotril)FDA LinkGeneric
11/2012 - 06/2009
2Sodium Channels (Sodium Channel)IBA
03/2004 - 03/2003
1rufinamideFDA Link
01/2022
1Transcription Factors (Transcription Factor)IBA
01/2022
1Protein Isoforms (Isoforms)IBA
01/2022
1MSX2 proteinIBA
01/2020
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
01/2020
1BenzodiazepinesIBA
12/2019
1Antipsychotic Agents (Antipsychotics)IBA
12/2019
1Quinidine (Chinidin)FDA LinkGeneric
02/2019
1PotassiumIBA
02/2019
1NAV1.2 Voltage-Gated Sodium ChannelIBA
01/2019
1Serum AlbuminIBA
12/2018
1C-Reactive ProteinIBA
12/2018
1Biological ProductsIBA
11/2018
1Cytochrome P-450 CYP3AIBA
01/2018
1CreatinineIBA
01/2018
1Phosphotransferases (Kinase)IBA
01/2018
1IsofluraneFDA LinkGeneric
01/2018
1Peptides (Polypeptides)IBA
11/2016
1LipidsIBA
11/2016
1HDL CholesterolIBA
11/2016
1CholesterolIBA
11/2016
1AntibodiesIBA
11/2016
1Glutamate Receptors (Glutamate Receptor)IBA
11/2016
1N-Methylaspartate (NMDA)IBA
11/2016
1potassium bromideIBA
06/2016
1Glutamine (L-Glutamine)FDA Link
12/2015

Therapy/Procedure

20Therapeutics
01/2022 - 03/2003
8Electrodes (Electrode)
09/2017 - 08/2004
2Drug Tapering
12/2018 - 07/2015
2Ketogenic Diet
06/2016 - 07/2011
1Anesthesia
01/2018
1Vagus Nerve Stimulation
09/2017